Risk Factor Reduction

• Link to http://www.internalmedicinenews.com/article/PIIS1097869005726111/fulltext
  for an article appearing in the January 2006 Internal Medicine News regarding cardiovascular risk associated with chronic kidney disease.

• The following article describes the increased risk of ESRD in obese patients: Obesity and risk of ESRD

• An example of the deleterious effect of anemia on survival in patients with congestive heart failure is noted here. Chronic Kidney Disease (CKD) is a frequent cause of anemia in these patients.  As hemoglobin decreases (horizontal axis), 1-year mortality risk increases (vertical axis):

The following is from the National Kidney Foundation’s Guidelines for the care of patients with chronic kidney disease (KDOQI).

Clinical Practice Guidelines

Guideline Development and Methodology

Disclaimer and Acceptable Use Policy

Published KDOQI Guidelines

• Clinical Practice Guidelines for Cardiovascular Disease in Dialysis Patients
  Primary Sponsor: Satellite Healthcare
  Implementation Sponsor: Genzyme
  Amgen is the Founding and Principal Sponsor of KDOQI
• Clinical Practice Guidelines on Hypertension and Antihypertensive Agents in Chronic Kidney Disease
  American Journal of Kidney Diseases, May 2004
  Primary Sponsor: Astra Zeneca
  Implementation Sponsor: Merck & Co., Inc
  Amgen is the Founding and Principal Sponsor of KDOQI
• Bone Metabolism and Disease in Chronic Kidney Disease
  American Journal of Kidney Diseases, October 2004
  Primary Sponsor: Abbott Laboratories
  Associate Sponsors: Amgen, Genzyme
  Implementation Sponsors: Abbott Laboratories, Amgen, Bone Care International, Genzyme, Shire US
  Amgen is the Founding and Principal Sponsor of KDOQI
• Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation Classification and Stratification
  American Journal of Kidney Diseases, February 2002
  Primary Sponsor: Amgen
  Implementation Sponsors: Bayer Diagnostics, OrthoBiotech Products, LP, UpToDate
  Amgen is the Founding and Principal Sponsor of KDOQI
• Managing Dyslipidemias in Chronic Kidney Disease
  American Journal of Kidney Diseases, April 2003
  Primary Sponsor: Fujisawa
  Amgen is the Founding and Principal Sponsor of KDOQI
• Clinical Practice Guidelines for Managing Dyslipidemias in Kidney Transplant Patients
  Am J Trans 2004:4 (Suppl. 7)
  Primary Sponsor: Fujisawa
  Amgen is the Founding and Principal Sponsor of KDOQI
• Executive Summaries of the Guidelines for Hemodialysis Adequacy; Nutrition in Chronic Renal Failure; Peritoneal Dialysis Adequacy; Treatment of Anemia of Chronic Kidney Disease; and Vascular Access (2000)
  Primary Sponsor: Amgen
  Amgen is the Founding and Principal Sponsor of KDOQI
• Hemodialysis Adequacy Update
  American Journal of Kidney Diseases, January 2001
  Primary Sponsor: Amgen
  Associate Sponsor: Luitpold Pharmaceuticals (American Regent)
  Implementation Sponsor: Watson Pharmaceuticals
  Amgen is the Founding and Principal Sponsor of KDOQI
• Peritoneal Dialysis Adequacy Update
  American Journal of Kidney Diseases, January 2001
  Primary Sponsor: Amgen
  Associate Sponsor: Luitpold Pharmaceuticals (American Regent)
  Implementation Sponsor: Watson Pharmaceuticals
  Amgen is the Founding and Principal Sponsor of KDOQI
• Treatment of Anemia of Chronic Renal Failure Update
  American Journal of Kidney Diseases, January 2001
  Primary Sponsor: Amgen
  Associate Sponsor: Luitpold Pharmaceuticals (American Regent)
  Implementation Sponsor: Watson Pharmaceuticals
  Amgen is the Founding and Principal Sponsor of KDOQI
• Vascular Access Update
  American Journal of Kidney Diseases, January 2001
  Primary Sponsor: Amgen
  Associate Sponsor: Luitpold Pharmaceuticals (American Regent)
  Implementation Sponsor: Watson Pharmaceuticals
  Amgen is the Founding and Principal Sponsor of KDOQI
• Nutrition in Chronic Renal Failure
  American Journal of Kidney Diseases, June 2000
  Primary Sponsor: Sigma Tau
  Sponsor: Baxter Healthcare, Fresenius USA
  Associate Sponsor: Luitpold Pharmaceuticals (American Regent)
  Implementation Sponsor: Watson Pharmaceuticals
  Amgen is the Founding and Principal Sponsor of KDOQI

Guidelines Under Development

• Diabetes and Chronic Kidney Disease
  Primary Sponsor: Amgen
  Amgen is the Founding and Principal Sponsor of KDOQI
• Update: Anemia and Chronic Kidney Disease
  Primary Sponsor: Amgen
  Implementation Sponsor: Watson
  Amgen is the Founding and Principal Sponsor of KDOQI
• Update: Peritoneal Dialysis Adequacy
  Associate Sponsors: Baxter, Fresenius and Genentech
  Amgen is the Founding and Principle Sponsor of KDOQI
• Update: Hemodialysis Adequacy
  Associate Sponsors: Baxter, Fresenius and Genentech
  Amgen is the Founding and Principle Sponsor of KDOQI
• Vascular Access
  Associate Sponsors: Baxter, Fresenius and Genentech
  Amgen is the Founding and Principle Sponsor of KDOQI